Chronic pain often leads to depression, which increases suffering and is clinically difficult to treat. Understanding the underlying mechanism identifies a potential therapeutic target for treatment. </p><div> Written by: Jeff Hansen and Anna Jones<br/> Media contact: Jeff Hansen<p><span class=”wf_caption” style=”margin-bottom: 10px; margin-left: 20px; float: right; display: inline-block; max-width: 450px;” role=”figure”><img src=”https://news.google.com/news/images/2018/Stream_antidepressant_in_chronic_pain.png” alt=”Stream antidepressant in chronic […]
Archive 2022 – Gene Mutations of Patients with Wasting Seizures and Movement Disorders Created in Mice
Findings from University of Maryland Medical School study provide new understanding of disease mechanism and treatment options Three genetic alterations associated with a rare seizure and movement disorder found primarily in children have been successfully bred in mice and their symptoms treated, in a new study by a researcher at the University of Medicine School […]
Aging can be reversed in mice. Are people next?
CNN — In Boston labs, old, blind mice have regained their sight, developed smarter, younger brains, and built healthier muscle and kidney tissue. On the flip side, young mice age prematurely, with devastating results for nearly every tissue in their bodies. The experiments show that aging is a reversible process capable of being driven “back […]
When alpha mice are defeated by weaklings, they go into depression | Science
When two male mice meet in a small space, the rules of the fight are clear: the lower placed mouse must yield. But when these norms go out the window, such as when researchers set up such a meeting to favor the weakling, it sends the higher-ranking man into a tailspin. That’s the conclusion of […]
Study: Blocking immunosuppressive cells in mice with glioblastoma improves survival
Patients with glioblastoma, a devastating and lethal form of brain cancer, receive treatment that often leads to the unfortunate side effect of low white blood cell counts lasting from six months to a year. Low white blood cell counts are associated with shorter survival – but the specific reason for the prolonged drop in white […]
Dual agents: modified bacteria fight pathogenic biofilms in mice
Mycoplasma pneumoniae are small bacteria commonly known to cause lung infections. But now, a group of scientists has turned them into double agents. genetically modified Mycoplasma helped to break down biofilms of another pathogenic microbe, Pseudomonas aeruginosain a mouse model of ventilator-associated pneumonia and in tube samples taken from human patients, the team reported on […]
Amino Acid Supplements Alleviate Nerve Damage in Diabetic Mice
Salk scientists discover that altered serine metabolism in diabetes leads to peripheral neuropathy – a discovery that may provide a new way to identify people at high risk and a potential treatment option About half of people with type 1 or type 2 diabetes have peripheral neuropathy – weakness, numbness and pain, particularly in the […]
Serine amino acid supplementation alleviates neuropathy in diabetic mice
‘Gentle’ Islet Cell Transplant Cures Mice With Diabetes With Few Side Effects, Stanford Medicine Researchers Say Information Center
Other studies by Strober and others, including study co-author and professor of medicine Judith Shizuru, MD, PhD, have shown that it is possible to hinder, rather than eliminate, the immune system of the recipient before introducing the donor stem cells. The result is a hybrid immune system, composed of both donor and recipient stem cells, […]
Scientists heal scars caused by heart attack in mice: study
It may not be possible to mend a broken heart, but scientists have taken a new step towards healing the scars of one. An international team of researchers restored, for the first time, elasticity in the scarred tissue of the hearts of mice, injecting them with a specific protein. “What we found is highly encouraging,” […]