KAIST (President Kwang Hyung Lee) announced on January 30th that a research team led by Professor Kwang-Hyun Cho of the Department of Bio and Brain Engineering was able to use systems biology research to alter the properties of cancer cells in the lungs and eliminate drug resistance and their ability to proliferate to other areas […]
Impact of AMPK on progression and metastasis of cervical carcinoma
The main objective of this study was to correlate AMPK expression and activation with the acquisition of invasive capabilities through the implementation of EMT. Our findings revealed that AMPK expression is related to the malignant behavior of CC cells. In the C-4I cell line, AMPKα expression and activation remain at a higher level than in […]
New molecular pathway critical for the initiation of pancreatic tumors discovered
Researchers at the University of California San Diego School of Medicine have discovered a molecular pathway that is crucial for the initiation of pancreatic tumors. The mechanism may also contribute to the disease’s high resistance to chemotherapy and its propensity to metastasize. The study was published on 16 January 2022 in Nature’s Cell Biology, found […]
Study reveals molecular features responsible for development and progression of metastatic breast cancer
A multi-institutional national study identified unique molecular features responsible for the development and progression of metastatic breast cancer. One of the main features involves changes in the immune system due, in part, to methylation of the HLA-A gene; methylation is the addition of a small chemical group to a DNA molecule. Focal deletions, or the […]
Anti-anxiety drugs reduce metastasis rate after tumor removal
After the primary colon cancer tumors were surgically removed from 34 patients, 16 of them received a short, simple two-drug treatment developed at Tel Aviv University, which has been proven to dramatically reduce the risk of the cancer spreading (metastasis). Typically, the risk of metastases after tumor removal is around 35 percent among patients with […]