Metabolic

Artificial neural network shows promise for predicting neonatal metabolic bone disease

Artificial neural network (ANN) may be an efficient tool for predicting neonatal metabolic bone disease (MBD) during prenatal and postnatal periods according to a recent study. MBD is commonly seen in babies born prematurely who lack fetal mineral accumulation. Hypophosphataemia, hyperphosphataemia and skeletal demineralization are all hallmarks of MBD. Osteopenia, osteoporosis, rickets, and pathologic fractures […]

Soy protein blocks the production of LDL cholesterol, reducing the risk of metabolic diseases

A protein found in soybeans blocks the production of a liver enzyme involved in the metabolism of triglycerides and low-density lipoprotein (LDL), results of a study published in Antioxidants showed. Consuming soybean meal rich in B-conglycinin could potentially lower LDL cholesterol levels and lower the risk of metabolic diseases, such as atherosclerosis and fatty liver […]

Research offers hope for patients affected by a rare, inherited metabolic disease

New research offers potential benefits for those affected by the inherited metabolic disease methylmalonic aciduria. By combining the results of several molecular analyses, researchers can better diagnose this rare and serious disease. In the future, an improved understanding of the disease may also improve treatment options. Methylmalonic aciduria (MMA) is a metabolic disorder that affects […]

Could B vitamins protect against metabolic syndrome?

Data published in Open JAMA Networksuggest that adequate intakes of folate, vitamin B6, and vitamin B12 should be recommended for the prevention of MetS. “We found that folate intake was inversely associated with all individual components of MetS,” write the scientists. “However, the inverse association between vitamin B6 and MetS can be explained primarily by […]

Cardiovascular and Metabolic Disease Research at Novartis

With new tools and approaches comes a broader opportunity to benefit patients. Cardiovascular and metabolic diseases are responsible for an estimated 18 million deaths worldwide each year and represent an enormous burden on individuals and society. Our cardiovascular and metabolic disease researchers are developing a diverse portfolio of approaches to prevent, delay or reverse these […]

WSU Scientists Discover New Stress Hormone That Counteracts Metabolic Disorders – School of Medicine News

The research team included, pictured from left, Hyunbae Kim, Ph.D., Kezhong Zhang, Ph.D., and Zhenfeng Song, Ph.D. A research team led by Professor Kezhong Zhang, Ph.D., at Wayne State University School of Medicine’s Center for Molecular Medicine and Genetics and the Department of Biochemistry, Microbiology and Immunology, has made an important discovery in a stress-induced […]

Metabolic syndrome associated with sleep duration, insomnia

Metabolic syndrome (MetS) is a disease diagnosed in people with metabolic abnormalities, such as hypertension and abdominal obesity. Short and long sleep duration are known predictors of adverse medical outcomes. A study published in BMC endocrine disorders found that sleep duration and insomnia had an effect on the current and future risk of MetS in […]

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