Poor vision condition linked to serious heart problems; Benefits of exercising in the morning; and FDA warns consumers about some dietary supplements

Age-related poor vision may signal serious types of cardiovascular disease, researchers find

A specific form of age-related macular degeneration (AMD), a leading cause of blindness in the US, may indicate that the patient also has serious cardiovascular problems, such as heart failure and carotid artery disease, according to new research in the New York Eye and Ear Infirmary of Mount Sinai, New York.

The research, published in the BMJ Open Ophthalmology🇧🇷 is considered the first to specify which types of high-risk cardiovascular and carotid diseases are associated with the eye disorder. The findings could lead to increased screening to save sight, diagnose undetected heart disease and prevent life-threatening cardiovascular events, including heart attacks and certain types of strokes.

“This study is the first strong link between the leading cause of blindness, AMD and heart disease, the leading cause of death worldwide,” explains lead author R. Theodore Smith, MD, Ph.D., professor of ophthalmology at the Icahn School of Medicine at Mount Sinai, in a press release.

AMD, which is common, is the leading cause of visual impairment and blindness in people over age 65. It is usually diagnosed after damage to the central area of ​​the retina called the macula. the macula is the part of the eye that processes what is directly in front of it (or central vision) and is vital for general vision. Blurred vision is a key symptom of AMD.

Furthermore, adds Dr. Smith, the researchers now have “strong evidence” for what causes this association. “Blood supply to the eye is directly diminished by these diseases, whether it be damage to the heart that decreases blood supply throughout the body, or a blocked carotid artery that directly impedes blood flow to the eye.”

One type of early AMD, known as subretinal drusenoid deposits (SDDs), requires high definition retinal images to detect. These deposits contain a form of cholesterol found beneath the light-sensitive retinal cells, where damage occurs and vision is lost. There is no known treatment for SDDs. The Mount Sinai research team initially found that patients with cardiovascular disease or stroke were more likely to have SDDs. This research was published in the July issue of Retina

In the new study, which expands on their previous work, researchers found that AMD patients with severe cardiovascular disease and stroke were nine times more likely to have SDDs, compared with patients without these serious heart conditions.

“This work demonstrates the fact that ophthalmologists may be the first clinicians to detect systemic disease, especially in asymptomatic patients,” said co-investigator Richard B. Rosen, MD, chief of the Retina Service at Mount Sinai Health System, in an announcement. 🇧🇷

Exercising in the morning may lower your risk of heart disease and stroke more than being active later in the day, new study finds

Regular exercise has many health benefits, including reducing the risk of many chronic diseases. But is there a specific time of day when physical activity is most beneficial? New research has linked morning exercise with a lower risk of heart disease and stroke.

So says a study of more than 85,000 individuals published in the European Journal of Preventive Cardiology🇧🇷 The results were consistent regardless of the total amount of daily activity.

“It’s well established that exercise is good for heart health, and our study now indicates that morning activity appears to be more beneficial,” said study author Gali Albalak of Leiden University Medical Center in the Netherlands in an announcement. “The findings were particularly pronounced in women and applied to both early risers and night owls.”

The study used the UK Biobank database and included 86,657 adults, aged between 42 and 78 years, initially free of cardiovascular disease. The median age was 62 years and 58 percent were women. Participants wore an activity tracker on their wrist for seven consecutive days. Participants were followed for incident cardiovascular disease, “which was defined as the first hospitalization or death related to coronary artery disease or stroke.”

The researchers followed for six to eight years. They found that 2,911 participants developed coronary artery disease and 796 had a stroke. Being most active between 8 am and 11 am was associated with the lowest risks of heart disease and stroke.

In a second review of the data, the researchers divided participants into four groups based on peak physical activity times: 1) noon; 2) early morning 3) late morning; and 4) night. After adjusting for age and gender, participants who were most active in the early morning or late morning had 11% and 16% lower risk of incident coronary artery disease, respectively, compared with those with peak hours in the middle of the day or at the end of the day. frames. What’s more, those who were most active in the late morning had a 17% reduction in their risk of stroke.

FDA warns public not to use dietary supplements claimed to treat heart disease

The U.S. Food and Drug Administration (FDA) has issued warning letters to seven companies for “illegal sale of dietary supplements that claim to cure, treat, mitigate or prevent cardiovascular disease or related conditions, such as atherosclerosis, stroke or heart failure”.

The FDA states that it “is urging consumers not to use these or similar products because they have not been evaluated by the FDA as safe or effective for their intended use and may be harmful.”

The FDA recommends that consumers talk with their physicians before deciding to use any dietary supplement or medication. Some supplements may interact with medications or other supplements. “Healthcare professionals will work with patients to determine which treatment is the best option for their condition,” the FDA said.

Warning letters and company names can be found at this link.

“Given that cardiovascular disease is the leading cause of death in the US, it is important that the FDA protect the public from products and companies that make illegal claims to treat it,” said Cara Welch, Ph.D., director of the Office of Dietary Supplement Programs at the FDA’s Center for Food Safety and Applied Nutrition, in a statement. “Dietary supplements that claim to cure, treat, mitigate or prevent cardiovascular disease and related conditions may harm consumers who use these products instead of seeking safe and effective FDA-approved treatments from qualified healthcare professionals.”

The FDA says it requested prompt responses from companies “stating how they will address the issues described in the warning letters or provide their reasons and supporting information about why they think the products do not violate the law.”

Tags: exercise and fitness, eye health, heart disease

Poor vision condition linked to serious heart problems; Benefits of exercising in the morning; and FDA warns consumers about some dietary supplements

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