The Illinois Institute of Technology is one of 14 institutions selected as a registry site for the National Institute of Health’s landmark initiative to advance nutrition research. Nutrition for Microhealth (NPH), powered by all of us The research program engages 10,000 participants from diverse backgrounds across the United States with the goal of learning how our bodies respond differently to food.
NPH will use AI-based methods to analyze information provided by participants in order to develop algorithms that predict responses to dietary patterns. The results of the study may one day allow healthcare providers to provide personalized dietary guidelines to improve overall health.
“Poor diet is one of the leading causes of preventable disease and death worldwide,” said Holly Nicastro. “If everyone follows the healthy eating guidelines we have now, we may not achieve optimal health because our bodies respond differently to food.” , Ph.D., MPH, NPH Coordinator. “With this study, we look forward to better understanding differences in individual responses and paving the way for more personalized guidance in the future.”
Illinois Tech, in collaboration with Northwestern University and the University of Chicago, will leverage the Illinois Precision Medicine Consortium (IPMC) to help all of us Participants in the research program join an investigation into the determinants of distinct dietary patterns after assessing the subjects’ usual diet and their body’s response to a standard meal challenge. A comprehensive analysis of people’s blood, urine, and gut microbiome under different diets—along with factors including genes, lifestyle, health history, and social determinants of health—will feed into densely rich data to enable predictive AI models to create personalized diet recommendations to reduce public health problems such as obesity and seizures. Blood pressure, diabetes and more.
“We are excited to be part of this revolutionary project that uses the latest analytical and computational technologies and engages diverse communities in the scientific process of the Technology Division of Food Science and Nutrition,” says Brett Burton Freeman, professor and director of the Nutrition Research Center and President of the Illinois Department of Technology. Everyone,” and through this study, we hope to glean insights that will lead to more personalized dietary guidelines, empowering individuals to make food and nutritional choices that best serve their health and well-being. ”
To participate in NPH, individuals must be 18 years of age or older and must be registered or already registered with the National Institutes of Health all of us Research program (link is external). all of us It is an effort to engage at least 1 million participants in building a health database that reflects the diversity of the United States, to help accelerate medical research and enable individualized prevention, treatment, and care options.
An NPH study consists of three components. All study participants will participate in the first component, while a subgroup will participate in the other two components. In the first component of the study, participants will be asked to complete surveys, report on their daily diets, and submit blood, urine, and stool samples for laboratory testing, including microbiome analysis. In the second component, a subset of participants will be given diets chosen by the researchers. In the third component, participants will also be given diets chosen by the researchers but will be required to stay in a research center while they follow the diets. Participants from all three components of the study will participate in meal challenge tests that measure biological changes after they have consumed a standard study-provided meal or beverage. Participants will receive annotated information from the study about their health, including body fat percentage, microbiome makeup, metabolism, and diet composition.
NPH will correlate participant data from the study with information obtained through all of us Research program, including genetic information and data from electronic health records and additional surveys. The study will take advantage of advances in artificial intelligence to analyze this vast amount of data from participants to develop algorithms that predict how a person will respond to a particular food or diet based on various factors. All of this data will eventually be accessed through all of us’ Data platform, Researcher Work Platform (link is external), to support many other studies on health and disease. Strict safeguards are in place to maintain data security and protect participants’ privacy.
“Nutrition is perhaps one of the most powerful medicines we have, but it is among the least understood,” said Jeffrey Ginsburg, MD. all of us’ Medical and scientific officer. by tapping on all of us Infrastructure and platform, NPH will be distinguished from other nutrition studies by its size and diversity. The value of NPH will be amplified by the research community as new data types are widely made available in the Researcher Workbench to explore and advance our understanding of nutrition and health. ”
Illinois Institute of Technology