DefenAge® Skincare Announces Defensin Master Anti-Aging Patent for Signature Cell Stimulating Technology

DefenAge is celebrating with HUGE Black Friday discounts

CARLSBAD, California, November 25, 2022 /PRNewswire/ — DefenAge® Skincare, manufacturer and distributor of revolutionary, evidence-based anti-ageing products, announces the new Defensin Master Anti Aging Patent issued by the US Patent Office (Patent #11,491,096).

Seven years in the making, the new patent recognizes DefenAge’s groundbreaking cell-stimulating compositions and methods to create fresh, new skin. This leading patent concludes DefenAge’s international family of patents for using Defensin molecules to reverse signs of skin aging on a global scale – including a reduction in visible fine and coarse wrinkles, pore size and pigmentation.

The patent supports that Defensin technology is extremely effective in combating almost all signs of skin aging and is an excellent solution as an anti-aging treatment for both men and women. At the heart of the patented technology is the unique ability of Defensin molecules to activate the body’s most powerful regenerative response by activating dormant, “preserved” young skin master cells to generate new, young skin.

Renowned Dermatologist, Natalie M CurcioMD, MPH, MMHC (Nashville, Tenn) details, “Defensins are unique natural molecules that trigger a regenerative response in the skin, similar to the one our bodies generate during wound healing. Each time a scratch or wound on the skin heals, the skin in the healed (closed) wound area is always younger than the skin around it. This is because our body activates “preserved” young cells to heal wounds. In other words, the body produces new, young skin to repair wounds. Defensins activate the same mechanism in our body, which means that every time defensins are applied to the skin, they activate the body to produce new and young skin without wounds.”

Defensins activate dormant preserves of “fresh” cells in the body, LGR6-positive skin master cells. Upon activation, LGR6-positive cells physically migrate to the basal layer of the skin, creating a new epidermis and ultimately new, younger-looking skin, providing all the benefits of retinols without irritation, inflammation or sun sensitivity.

Well-known dermatologist, Dr. Suneel Chilukuri (Houston, Texas) weighs in on the clinical evidence, saying, “DefenAge is one of the most rigorously tested and proven modern cosmeceutical products you can find. DefenAge’s products and their defensins were tested in 19 clinical studies, including those published in the best peer-reviewed journals, the Journal of Drugs in Dermatology and Journal of Cosmetic Dermatology. The studies show that every part of the skin is able to respond to defensins, improving a variety of skin qualities that address nearly all aspects of visible skin aging, including the face, the skin around the eyes and the body. Even the scalp and the skin under the hair improve and normalize hair growth rates.”

The quality and wide range of results are also appreciated by consumers. A 2022 consumer survey with more than 850 responses from verified buyers indicated that 94 percent of respondents said they were satisfied with the results they see with DefenAge, 97 percent said they would buy DefenAge again, and 91 percent said DefenAge is a plays a key role in their skincare routine.


To give everyone a chance to experience the power of Defensins, DefenAge launched a massive Black Friday sale: BOGO 65 percent OFF along with offering multiple free trial products and an additional 25% off all products when customers join the DefenAge Skin Club Rewards Program. Visit to take advantage of these high discounts (valid November 25-28e).

A portion of the proceeds from DefenAge’s Black Friday sale will go towards a donation to the Monarch School of San Diego to enrich the lives of helping underserved and at-risk students from kindergarten through 12th grade gain the stability and security they need to learn and thrive.

About DefenAge®:

DefenAge is an American company founded in 2014 by a team of regenerative medicine experts whose anti-aging discovery became the heart and soul of its formulas. DefenAge products are widely recommended by dermatologists as a high quality, anti-aging cosmetic skin care for visible skin rejuvenation and as a safe alternative to retinol. DefenAge meets or exceeds Clean Beauty standards and its products are never tested on animals. Honesty, transparency and excelling in every way are the company’s standards. DefenAge shows an industry-leading consumer purchase rate.



DefenAge® Skincare Announces Defensin Master Anti-Aging Patent for Signature Cell Stimulating Technology

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